Understanding Heart Disease
Heart disease remains the leading cause of death worldwide, encompassing conditions such as coronary artery disease, heart failure, cardiomyopathy, and post-infarction damage. When heart tissue is damaged by reduced blood flow or a heart attack, it is typically replaced by scar tissue that cannot contract or conduct electrical signals.
This scarring reduces the heart's pumping efficiency (ejection fraction), leading to heart failure symptoms including shortness of breath, fatigue, fluid retention, and exercise intolerance. Current treatments include medications, stents, bypass surgery, and in severe cases, heart transplantation.
Regenerative medicine offers an emerging approach to cardiac care, with MSC therapy showing potential to support heart muscle repair, improve blood vessel formation, and reduce the inflammatory processes that contribute to ongoing cardiac damage.
Common Symptoms
- Shortness of breath during activity or at rest
- Chest pain or pressure (angina)
- Fatigue and reduced exercise capacity
- Swelling in legs, ankles, and feet
- Rapid or irregular heartbeat
- Persistent cough or wheezing
How MSC Therapy May Help
MSCs may support cardiac health through multiple pathways. They release paracrine factors including VEGF, HGF, and IGF-1 that promote new blood vessel formation (angiogenesis) in ischemic heart tissue. Improved blood supply to damaged areas may help restore function to hibernating cardiomyocytes, heart cells that are alive but not functioning due to inadequate blood flow.
The anti-inflammatory properties of MSCs may help reduce the chronic inflammation that drives progressive cardiac remodeling and fibrosis after heart injury. By modulating the immune response in cardiac tissue, MSCs may help create a more favorable environment for healing and reduce further scar formation.
Preclinical and clinical studies suggest that MSCs may also support the survival and function of existing heart muscle cells while promoting the differentiation of cardiac progenitor cells. These combined effects may contribute to measurable improvements in ejection fraction and functional capacity.
Our Treatment Approach
Cardiac Evaluation
Comprehensive cardiac assessment including echocardiography, ejection fraction measurement, and cardiovascular risk profiling to design a personalized treatment protocol.
IV MSC Infusion
Systemic intravenous delivery of MSCs to promote angiogenesis, reduce cardiac inflammation, and support heart muscle repair throughout the cardiovascular system.
Vascular Support Therapy
Complementary exosome therapy and treatments targeting improved endothelial function and vascular health to enhance cardiac blood supply.
Cardiac Rehabilitation
Guided exercise recommendations, nutritional optimization for heart health, and ongoing monitoring of cardiac function and biomarkers.